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Hugh LaurieSam Bell
Joely RichardsonLucy Bell
Adrian LesterGeorge
Matthew MacfadyenNigel
Yasmin BannermanMelinda
Joanna LumleyShiela
Rowan AtkinsonMr. James
Emma ThompsonDruscilla
James PurefoyCarl Phipps
Tom HollanderEwan Proclaimer
Rachael StirlingJoanna
Dave ThompsonDave the Comedian / Mrs. Furblob- Stephen SimmsTrevor
- John BrennerKit
- Jaz WilsonBaby Cuthbert
Richard LeafJustin Cocker
Paul ReadyStudent Doctor
John LightbodyHospital Administrator
Mina AnwarYasmin
John FortuneAcupuncturist
Kelly ReillyNimnh
Dawn FrenchCharlene- Serena EvansDr. Cooper
Lisa PalfreyJan
Judi ShekoniEwan's Posse- Lidija ZovkićPetra