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Asia ArgentoSarah
Jimmy BennettYoung Jeremiah
Jeremy RennerEmerson
Winona RyderPsychologist
Ornella MutiGrandmother
Peter FondaGrandfather
Dylan SprouseOlder Jeremiah- Kara KempSocial Worker #1
Cole SprouseOlder Jeremiah
Kip PardueLuther
Ben FosterFleshy Boy
Matt SchulzeKenny
Michael PittBuddy- Brent AlmondCop #1
David DwyerCop #2- David Brian AlleyDoctor (as David Alley)
Marilyn MansonJackson
Savannah Knoop
Lydia LunchSocial Worker #2
Tim ArmstrongStinky
John RobinsonAaron
Jeremy SistoChester