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Julianne MooreAlice Howland
Kate BosworthAnna Howland-Jones
Shane McRaeCharlie Howland-Jones
Hunter ParrishTom Howland
Alec BaldwinJohn Howland
Seth GilliamFrederic Johnson
Kristen StewartLydia Howland
Stephen KunkenDr. Benjamin
Erin DarkeJenny
Daniel GerrollEric Wellman
Quincy Tyler BernstineNursing Home Administrator- Maxine PrescottNursing Home Resident
Orlagh CassidyPrimary Care Doctor
Rosa ArredondoConvention Facilitator
Zillah GloryMasha (Three Sisters)
Caridad MontanezElena- Caleb FreundlichYoung Musician
- Charlotte RobsonYoung Musician
- Jean BurnsOlga (Three Sisters) (sem créditos)
José BáezHead Waiter (sem créditos)
Victoria CartagenaProf. Hooper (sem créditos)- Jeannette GouldAlzheimer's Patient (sem créditos)
Takako HaywoodAlzheimer's Conference Attendee (sem créditos)- Samantha KellyTV Reporter (sem créditos)
- Diane KimbrellAlzheimer's Patient (sem créditos)
- Cat LynchPinkberry Worker (sem créditos)
Joanne PericaCrying Woman (sem créditos)- Jamie Lee PetronisPinkberry Worker (sem créditos)
Nancy Ellen ShoreNurse (sem créditos)
Eha UrbsaluAlice's Mother (sem créditos)- Gail YudainMeeting Attendee (sem créditos)
- Cal FreundlichYoung Musician