Sherlock Holmes
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William GilletteSherlock Holmes
Ernest MaupainProfessor Moriarty- Marjorie KayAlice Faulkner
Edward FieldingDr. Watson- Stewart RobbinsBenjamin Forman
Hugh ThompsonSir Edward Leighton- Ludwig KreissBaron von Stalburg
- Mario MajeroniJames Larrabee
- William PostanceSidney Prince
- Chester BeeryCraigin
Fred Malatesta'Lightfoot' McTague
Grace RealsMadge Larrabee- Leona BallTherese
- Burford HampdenBilly
- Marian SkinnerA Suffragette
Edward ArnoldMoriarty Henchman In Striped Cap- Frank HamiltonTim Leary