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Joaquin PhoenixJohnny
Gaby HoffmannViv
Woody NormanJesse
Scoot McNairyPaul
Molly WebsterRoxanne
Jaboukie Young-WhiteFern
Deborah StrangCarol- Sunni PattersonSunni
Jenny EliscuWaitress
Mary PasseriBehavioral Center Nurse
Brandon RushER Nurse- Brey'on ShawBrey'on / New Orleans Interviewee
- Todd D'AmourParade Bystander 1
Beth BartleyParade Bystander 2- Artrial ClarkParade Bystander 3
- Eleanor Halm SimmonsParade Bystander 4
Keisuke HoashiDr. Hora- Maximilla LukacsViv's Friend 1
- Nancy GellViv's Friend 2
Gita ReddyDr. Rao
Mya GonzalesDetroit Kid 1- Cooper Jack RubinDetroit Kid 2
- Faith SteptoreNOLA School Teacher
- Mahfuzul IslamPharmacy Employee
- Na'kyah AdjumanDetroit Interviewee
- Jayce GarrettDetroit Interviewee
- Adilem HernandezDetroit Interviewee
- Joye PyronneauDetroit Interviewee
- Malik PyronneauDetroit Interviewee
- Tallulah SmithDetroit Interviewee
- Tobias CenNew York Interviewee
- Ambar PerezNew York Interviewee
- Dora DulgeNew York Interviewee
- Roselin GarciaNew York Interviewee
- Louie NathanNew York Interviewee
- Evan OrtizNew York Interviewee
Sophie Suzuki ShihNew York Interviewee- Tamar TanisNew York Interviewee
- Elvies YuanNew York Interviewee
- Devante BryantNew Orleans Interviewee
- Ethan ClubbNew Orleans Interviewee
- Robin HandNew Orleans Interviewee
- London HicksNew Orleans Interviewee
- Rayne KingNew Orleans Interviewee
- May MaczkaNew Orleans Interviewee
- Steven StewartNew Orleans Interviewee
- Chrisette ThompsonNew Orleans Interviewee
Leslie FeistWah Vocals (voz)
Elaine KaganSarah Klein (sem créditos)- Kate AdamsViv's Friend (sem créditos)
- Joseph BishopDancing Guy (sem créditos)
Callan FarrisDetroit Kid (sem créditos)- Khadija Emma NeumannDetroit Kid (sem créditos)